azelastine will increase the degree or impact of isavuconazonium sulfate by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.azelastine will enhance the level or influence of lemborexant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Intently. Reduce nightly dose of lemborexant advisable if